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Chemonucleolysis failures treated by PLIF.

R Sepulveda, A P Kant

    Clinical Orthopaedics and Related Research
    |March 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Chemonucleolysis offers significant sciatic pain relief, but failures may occur. Posterior Lumbar Interbody Fusion (PLIF) can effectively treat persistent symptoms in these cases.

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    Area of Science:

    • Neurosurgery
    • Orthopedic Surgery
    • Pain Management

    Background:

    • Chemonucleolysis involves enzyme injection into intervertebral discs to treat sciatic pain.
    • Reported success rates for chemonucleolysis range from 70% to 90%.

    Observation:

    • Chemonucleolysis failures can stem from free fragment removal via lumbar laminectomy.
    • A notable portion of failures are linked to spinal instability or neural foramen nerve root compression.

    Findings:

    • Posterior Lumbar Interbody Fusion (PLIF) was observed in 17 cases of failed chemonucleolysis.
    • PLIF demonstrated efficacy in alleviating pain and associated symptoms.

    Implications:

    • PLIF offers a viable treatment option for patients experiencing persistent symptoms after chemonucleolysis.

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  • This suggests PLIF can address specific failure mechanisms like instability and foraminal stenosis.