Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antibiotic infection prophylaxis in gallbladder surgery--a prospective randomized study.

B M Harnoss, A Hirner, M Krüselmann

    Chemotherapy
    |January 1, 1985
    PubMed
    Summary

    Preoperative ceftriaxone prophylaxis significantly reduced surgical site infections in patients undergoing cholelithiasis surgery. This antibiotic intervention prevented wound healing complications in the study group.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Cost-effectiveness of hernia repair : IPOM versus open sublay mesh technique].

    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2011
    Same author

    Impact of CCR7 on the gastrointestinal field effect.

    American journal of physiology. Gastrointestinal and liver physiology·2011
    Same author

    Secondary surgery subsequent to distal pancreatectomy.

    Hepato-gastroenterology·2010
    Same author

    Perioperative infliximab application ameliorates acute rejection associated inflammation after intestinal transplantation.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2010
    Same author

    [Heterozygous alpha-1-antitrypsin deficiency (PiMZ): risk factor in the development of primary liver carcinoma in non-cirrhotic liver?].

    Zeitschrift fur Gastroenterologie·2010
    Same author

    [Intrathoracic kidneys : review and case report].

    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2010

    Area of Science:

    • Surgical prophylaxis
    • Infectious disease
    • Clinical microbiology

    Background:

    • Cholelithiasis (gallstones) often necessitates surgical intervention.
    • Surgical site infections (SSIs) are a common complication following abdominal surgery.
    • Antibiotic prophylaxis is a standard measure to prevent SSIs.

    Purpose of the Study:

    • To evaluate the efficacy of preoperative ceftriaxone in preventing infectious complications after cholelithiasis surgery.
    • To compare SSI rates between patients receiving antibiotic prophylaxis and those not receiving it.

    Main Methods:

    • Prospective randomized study involving 180 patients undergoing elective cholelithiasis surgery.
    • Intervention group received 2g intravenous ceftriaxone preoperatively.

    Related Experiment Videos

  • Control group received no antibiotic prophylaxis.

    • Main Results:

    • Infectious wound healing disturbances occurred in 11% of the control group.
    • No infectious complications were observed in the ceftriaxone prophylaxis group.
    • The observed difference in infection rates was statistically significant.

    Conclusions:

    • Preoperative intravenous ceftriaxone is highly effective in preventing surgical site infections in patients undergoing cholelithiasis surgery.
    • Routine antibiotic prophylaxis with ceftriaxone should be considered for patients undergoing elective cholelithiasis procedures.
    • This strategy significantly improves postoperative wound healing outcomes.