Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nanoparticle-Based Biomaterials in Cancer Research: From Mechanistic Insights to Therapeutic Innovation.

International journal of molecular sciences·2026
Same author

Beyond Source Restrictions: Combined Mitigation Strategies Substantially Reduce Emissions and Exposure of Intentionally Added Microplastics in the UK.

Integrated environmental assessment and management·2026
Same author

Abiotic Hydrolysis of Microplastics: Influence of Polymer Chain Scission on Particle Fragmentation and Dissolved Organic Carbon Release.

Environmental science & technology·2026
Same author

Si<sub>3</sub>N<sub>4</sub> Microring Resonator-Based Refractive Index Sensing for Liquid Samples: Comparing Wavelength Scanning and Fixed-Wavelength Probing.

ACS measurement science au·2026
Same author

Flow Injection-Based Refractive Index Sensing with a Si<sub>3</sub>N<sub>4</sub> Photonic Crystal Nanobeam-Microring Fano Resonator.

ACS applied optical materials·2026
Same author

Molecules in Wikipedia: Analysis of Their Chemical Diversity, Functional Roles, and Popularity.

Journal of chemical information and modeling·2025

Related Experiment Video

Updated: May 11, 2026

Microfluidic Applications for Disposable Diagnostics
10:21

Microfluidic Applications for Disposable Diagnostics

Published on: February 3, 2008

8.9K

Reagent storage and delivery on integrated microfluidic chips for point-of-care diagnostics.

Manoochehr Rasekh1, Sam Harrison2, Silvia Schobesberger3

  • 1College of Engineering, Design and Physical Sciences, Brunel University London, Uxbridge, UB8 3PH, UK. manoochehr.rasekh@brunel.ac.uk.

Biomedical Microdevices
|June 2, 2024
PubMed
Summary

Microfluidic point-of-care diagnostics require efficient reagent storage and delivery. This review examines on-chip and off-chip methods, highlighting challenges and solutions for integrated microfluidic devices.

Keywords:
MicrofluidicsMicropumpsMicrovalvesPoint-of-careReagent storage

More Related Videos

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

11.8K
Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases
10:16

Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases

Published on: August 16, 2024

1.1K

Related Experiment Videos

Last Updated: May 11, 2026

Microfluidic Applications for Disposable Diagnostics
10:21

Microfluidic Applications for Disposable Diagnostics

Published on: February 3, 2008

8.9K
Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

11.8K
Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases
10:16

Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases

Published on: August 16, 2024

1.1K

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Point-of-Care Diagnostics

Background:

  • Microfluidic devices offer automated, miniaturized, and integrated solutions for rapid on-site biomarker detection.
  • Effective reagent storage and delivery are critical for multi-step microfluidic diagnostic processes, including sample preparation, nucleic acid extraction, amplification, and detection.

Purpose of the Study:

  • To review and discuss current methods for reagent storage and delivery in microfluidic point-of-care (POC) diagnostic systems.
  • To analyze the merits and limitations of both on-chip (self-contained) and off-chip (external) reagent storage solutions.
  • To provide guidelines for designing integrated microfluidic POC devices by considering microvalves and micropumps.

Main Methods:

  • Literature review of existing reagent storage and delivery approaches for microfluidic devices.
  • Categorization of storage solutions into direct on-chip and external storage methods.
  • Analysis of microvalves and micropumps relevant to integrated microfluidic systems.

Main Results:

  • A variety of approaches exist for reagent storage and delivery, but no universal solution is currently available.
  • Both on-chip and off-chip storage methods have distinct advantages and disadvantages that need careful consideration for specific applications.
  • The integration of microvalves and micropumps is crucial for controlling reagent flow and enabling complex sample preparation within microfluidic POC devices.

Conclusions:

  • Developing effective reagent storage and delivery systems is essential for advancing microfluidic point-of-care diagnostics.
  • Future research should focus on optimizing existing methods and exploring novel strategies to overcome current limitations.
  • Careful design incorporating appropriate microfluidic components will facilitate the development of robust and versatile integrated POC diagnostic devices.