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Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Related Experiment Video

Updated: Jun 24, 2025

Guidelines and Experience Using Imaging Biomarker Explorer IBEX for Radiomics
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Radiomics workflow definition & challenges - German priority program 2177 consensus statement on clinically applied

Ralf Floca1,2,3, Jonas Bohn4,5,6,7, Christian Haux8

  • 1German Cancer Research Center (DKFZ) Heidelberg, Division of Medical Image Computing, Heidelberg, Germany. r.floca@dkfz-heidelberg.de.

Insights Into Imaging
|June 2, 2024
PubMed
Summary
This summary is machine-generated.

Radiomics workflow definitions were standardized through expert consensus to overcome inconsistencies and support clinical translation. This work identifies key challenges for advancing radiomics adoption in healthcare.

Keywords:
Computer-assistedConsensus development conferenceImage processingTerminologyWorkflow

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Area of Science:

  • Medical Imaging Informatics
  • Radiomics Research
  • Clinical Workflow Standardization

Background:

  • Published radiomics workflow terminologies exhibit inconsistencies, hindering standardization and clinical translation.
  • Lack of standardized definitions is a major obstacle for the successful clinical adoption of radiomics.
  • Existing definitions lack a consensus, impeding reproducible research and widespread clinical implementation.

Purpose of the Study:

  • To achieve expert consensus on a definition for radiomics workflows, supporting clinical translation.
  • To identify and assess expert perspectives on critical challenges for implementing radiomics in clinical settings.
  • To establish a standardized terminology for radiomics studies.

Main Methods:

  • A multi-stage consensus process involving definition screening, semantic mapping of 22 workflow definitions, and a Delphi process with over 45 experts.
  • Retrospective analysis of 69 definition terms extracted from publications (2012-2020) to resolve semantic ambiguities.
  • Utilized a Delphi process with experts from the German Research Foundation (DFG) Priority Program 2177 to refine definitions and identify translational challenges.

Main Results:

  • A consensus definition for radiomics workflows, comprising seven phases and 37 aspects, was developed with high expert agreement (>89%).
  • Semantic ambiguities in 69 extracted terms were identified and resolved, leading to a standardized terminology.
  • Ten key challenges for clinical radiomics implementation were identified and characterized from expert perspectives.

Conclusions:

  • A consensus-based radiomics workflow definition and term mapping were compiled to address semantic inconsistencies and provide a reference terminology.
  • The study highlights critical challenges hindering the clinical application of radiomics, offering insights for future development.
  • Publicly available resources from this consensus effort can support the scientific community in advancing radiomics research and clinical integration.