Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Human Genetics01:28

Human Genetics

559
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
559
Introduction to Biological Bases of Psychology01:30

Introduction to Biological Bases of Psychology

3.2K
Biopsychology serves as a vital bridge connecting the intricate domains of biology and psychology, shedding light on how biological systems influence psychological phenomena. This field scrutinizes the biological substrates of behavior and mental processes, emphasizing the nervous system along with the roles of neurotransmitters, hormones, and genetics. It also incorporates evolutionary perspectives to explain the adaptive nature of mental functions.
The nervous system, the cornerstone of...
3.2K
Neurotransmitters01:31

Neurotransmitters

866
Neurotransmitters are essential chemical messengers within the nervous system, facilitating the communication between neurons. These chemical messengers, varying in function and effect, are critical for sustaining various aspects of neurological health and emotional well-being.
866
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

353
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
353
Biological Influences on Intelligence01:30

Biological Influences on Intelligence

89
Intelligence is often thought to be linked to brain size, but the relationship is more complex than that. While brain size does correlate modestly with some abilities, like verbal skills, the connection is weaker for others, such as spatial reasoning. Other factors, like brain structure, also play crucial roles. For instance, despite Einstein's smaller-than-average brain, his parietal cortex, which is involved in spatial reasoning, was 15% wider, suggesting that neural density might matter...
89
Relationship Formation02:12

Relationship Formation

40.0K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
40.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precision medicine in mental health: applications, challenges, and recommendations - CORRIGENDUM.

European psychiatry : the journal of the Association of European Psychiatrists·2026
Same author

Suicidality phenotypes reflect both shared and distinct genetic factors.

medRxiv : the preprint server for health sciences·2026
Same author

Thalamic nuclei volumes across psychiatric and neurological disorders: a multi-site magnetic resonance imaging study.

Translational psychiatry·2026
Same author

Perioperative risk factors for short- and long-term respiratory morbidity in patients with esophageal atresia.

Journal of pediatric surgery·2026
Same author

Precision medicine in mental health: applications, challenges, and recommendations.

European psychiatry : the journal of the Association of European Psychiatrists·2026
Same author

Immersive Technologies for Cognitive Rehabilitation in Dementia and Mild Cognitive Impairment: Systematic Review.

Journal of medical Internet research·2026
Same journal

Comparative Evaluation of Pretrained Large Language Models for Suicide Risk Prediction from Clinical Notes in U.S. Veterans.

medRxiv : the preprint server for health sciences·2026
Same journal

Nocturnal Respiratory Rate and Variability Predict Long-term Mortality in Stable Outpatients with Cardiovascular Disease.

medRxiv : the preprint server for health sciences·2026
Same journal

MOSAIC: Methylation-Oriented Site Analysis and Information Classifier for Robust Epigenomic Classification of Acute Leukemia in Clinical Cohorts with Variable Tumor Purity.

medRxiv : the preprint server for health sciences·2026
Same journal

Risk beliefs, intensive digital information and demand for a new preventative health product in public clinics: Evidence from an experiment in Zimbabwe.

medRxiv : the preprint server for health sciences·2026
Same journal

Development of an automated, imaging-based preoperative screening model for early identification of malnutrition in an abdominal surgery cohort.

medRxiv : the preprint server for health sciences·2026
Same journal

A Pilot Project Leveraging Large Language Models for Automated Screening and Variable Extraction in Observational Studies.

medRxiv : the preprint server for health sciences·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2025

Assessment of Social Interaction Behaviors
06:41

Assessment of Social Interaction Behaviors

Published on: February 25, 2011

93.2K

Shared genetics linking sociability with the brain's default mode network.

Giuseppe Fanelli1,2, Jamie Robinson3, Chiara Fabbri1

  • 1Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.

Medrxiv : the Preprint Server for Health Sciences
|June 3, 2024
PubMed
Summary
This summary is machine-generated.

This study reveals genetic links between sociability and brain

Keywords:
brain activitybrain connectivityexpression quantitative trait loci (eQTL)imaging geneticsneuroimagingsocial withdrawal

More Related Videos

Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions
10:45

Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions

Published on: July 6, 2011

11.6K
Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.3K

Related Experiment Videos

Last Updated: Jun 24, 2025

Assessment of Social Interaction Behaviors
06:41

Assessment of Social Interaction Behaviors

Published on: February 25, 2011

93.2K
Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions
10:45

Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions

Published on: July 6, 2011

11.6K
Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.3K

Area of Science:

  • Neuroscience
  • Genetics
  • Psychiatry

Background:

  • The brain's default mode network (DMN) is crucial for social cognition.
  • Altered DMN function is linked to social impairments in neuropsychiatric disorders.

Purpose of the Study:

  • To investigate the genetic relationship between sociability and DMN-related resting-state functional magnetic resonance imaging (rs-fMRI) traits.
  • To identify genes influencing both sociability and DMN function.

Main Methods:

  • Genome-wide association summary statistics for sociability and DMN rs-fMRI traits were analyzed.
  • Genetic correlations and bi-directional Mendelian randomization (MR) were performed.
  • Gene prioritization combined eQTL MR, CELLECT framework, and network propagation.

Main Results:

  • Significant local genetic correlations were found between sociability and DMN activity/connectivity traits.
  • Sociability influenced 12 rs-fMRI traits.
  • Seventeen genes were prioritized, with DRD2 and LINGO1 showing strong evidence.

Conclusions:

  • Genetic factors link sociability to specific DMN functional traits.
  • Prioritized genes like DRD2 and LINGO1 may be biomarkers for social dysfunction and potential drug targets.
  • Integrated genetic and transcriptomic data offer a strategy for future research.