Related Experiment Video
Updated: Apr 29, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Successful Collagen Crosslinking in a Patient With Keratoconus and Systemic Scleroderma
Ayman Alghamdi1, Essam A Alghamdi2, Abdullah Alghamdi3
1Oculoplastic Division, King Khaled Eye Specialist Hospital, Riyadh, SAU.
Abstract:
Scleroderma is an autoimmune disease that affects connective tissue. Keratoconus (KC) is a rare ocular condition that may appear alongside scleroderma. Contact lenses are an essential visual aid for KC patients, especially in advanced cases. However, scleroderma patients may face difficulties using them due to finger-related disabilities. Corneal collagen cross-linking (CXL) is a crucial treatment used to prevent corneal thinning and visual deterioration in progressive KC. However, the potential trigger of corneal melt and delayed healing following CXL in KC patients with scleroderma is a matter of concern. We present a case of a patient with KC and scleroderma who underwent CXL without any complications.
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