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Myasthenia Gravis Triggered by a COVID-19 Infection: A Case Report and Literature Review
Alexandra Mincă1,2, Dragos I Mincă3,4, Amalia L Calinoiu2
1Public Health, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU.
Abstract:
Myasthenia gravis (MG) is an autoimmune disease that induces skeletal muscle weakness, affecting different muscle groups. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), became both a diagnostic and a therapeutic challenge during the pandemic. The effects of COVID-19 are not only limited to the acute symptoms but also to the post-infectious sequelae. We present the case of a 30-year-old Caucasian woman, with no significant medical history, who presented to the emergency room with acute respiratory failure. The patient tested positive for SARS-CoV-2 with a rapid antigen test and during hospitalization developed a myasthenic crisis, ultimately being diagnosed with seropositive MG.
Insights
A COVID-19 infection triggered a myasthenic crisis in a previously healthy 30-year-old woman, leading to a diagnosis of seropositive myasthenia gravis (MG). This case highlights potential neurological complications of SARS-CoV-2.
Area of Science:
- Neurology
- Infectious Diseases
- Immunology
Background:
- Myasthenia gravis (MG) is an autoimmune disorder causing skeletal muscle weakness.
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses diagnostic and therapeutic challenges.
- COVID-19 can lead to post-infectious complications.
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