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Management of chronic kidney disease: The current novel and forgotten therapies
Ákos Géza Pethő1, Mihály Tapolyai2,3, Éva Csongrádi4
1Faculty of Medicine, Semmelweis University, Department of Internal Medicine and Oncology, Budapest, Hungary.
Insights
Chronic kidney disease (CKD) affects millions globally. While new treatments offer hope, early diagnosis and prevention are key to managing this incurable condition.
Area of Science:
- Nephrology
- Public Health
- Gerontology
Background:
- Chronic kidney disease (CKD) is a progressive, incurable condition impacting global health, particularly aging populations.
- Estimated to affect over 800 million people worldwide, CKD poses a significant health burden.
- Individuals with diabetes or hypertension face elevated risks of developing chronic kidney damage.
Purpose of the Study:
- To provide a narrative review of current therapeutic options for slowing the progression of chronic kidney disease (CKD).
- To highlight recent advancements in drug treatments and their impact on CKD management.
- To emphasize the critical importance of disease prevention and the need for further research in CKD.
Main Methods:
- A comprehensive literature search was conducted to identify relevant studies on CKD treatments.
- Narrative review methodology was employed to synthesize findings on therapeutic strategies.
- Focus was placed on summarizing available treatments and recent drug developments.
Main Results:
- Several new drug treatments have become available, offering new hope for CKD management.
- Dietary modifications and existing medications remain important for slowing disease progression.
- Early diagnosis is crucial for preventing complications associated with CKD.
Conclusions:
- While new treatments are promising, disease prevention remains the most critical aspect of CKD management.
- Significant public health impact necessitates further research into more effective diagnostic tools and treatments for CKD.
- Advancements in technology and medical knowledge are expected to improve future CKD care.
Abstract:
Chronic kidney disease (CKD) is a progressive and incurable condition that imposes a significant burden on an aging society. Although the exact prevalence of this disease is unknown, it is estimated to affect at least 800 million people worldwide. Patients with diabetes or hypertension are at a higher risk of developing chronic kidney damage. As the kidneys play a crucial role in vital physiological processes, damage to these organs can disrupt the balance of water and electrolytes, regulation of blood pressure, elimination of toxins, and metabolism of vitamin D. Early diagnosis is paramount to prevent potential complications. Treatment options such as dietary modifications and medications can help slow disease progression. In our narrative review, we have summarized the available therapeutic options to slow the progression of chronic kidney disease. Many new drug treatments have recently become available, offering a beacon of hope and optimism in CKD management. Nonetheless, disease prevention remains the most critical step in disease management. Given the significant impact of CKD on public health, there is a pressing need for further research. With the development of new technologies and advancements in medical knowledge, we hope to find more effective diagnostic tools and treatments for CKD patients.
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