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Related Experiment Video

Updated: Jun 24, 2025

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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Environment and arthritis.

Francesca Ruzzon1, Giovanni Adami2

  • 1Rheumatology Unit, University of Verona, Italy.

Clinical and Experimental Rheumatology
|June 3, 2024
PubMed
Summary
This summary is machine-generated.

Environmental factors like smoking, pollution, and diet significantly impact rheumatoid arthritis (RA) and immune-mediated inflammatory disorders (IMIDs). Understanding these triggers, including vitamin D and gut health, can aid in managing RA activity and severity.

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Area of Science:

  • Rheumatology and Immunology
  • Environmental Health Sciences

Background:

  • Rheumatoid arthritis (RA) and immune-mediated inflammatory disorders (IMIDs) have complex origins.
  • Environmental factors play a crucial role in the development and worsening of these conditions.

Purpose of the Study:

  • To review the multifactorial etiology of RA and IMIDs.
  • To emphasize the impact of environmental factors on disease pathogenesis and activity.

Main Methods:

  • Narrative review of existing literature.
  • Focus on modifiable environmental factors, weather, seasonality, vitamin D, diet, and the gut microbiome.

Main Results:

  • Cigarette smoking and air pollution are significant contributors to RA.
  • Weather, seasonality, and vitamin D levels influence RA activity.
  • Diet and gut microbiome alterations impact RA pathogenesis, with potential benefits from omega-3 fatty acids.

Conclusions:

  • Environmental factors are key drivers in RA and IMID development.
  • Potential for seasonal management and nutritional interventions exists.
  • Further research, including randomized clinical trials, is necessary to confirm clinical impacts.