Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

2.3K
Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
2.3K
Cell Motility through Blebbing01:16

Cell Motility through Blebbing

1.9K
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
1.9K
Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

2.5K
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
2.5K
Mechanism of Ciliary Motion01:05

Mechanism of Ciliary Motion

3.6K
The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities.
The cilia are made up of microtubules in a 9+2 arrangement, with nine microtubule doublet ring bundles, surrounding a pair of central singlet microtubule bundles. The doublet microtubule bundles are...
3.6K
Microtubules in Cell Motility01:24

Microtubules in Cell Motility

3.3K
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Resistance monitoring and putative biochemical mechanisms of Spodoptera frugiperda to different insecticides in China.

Pest management science·2026
Same author

The association between maternal FT3/FT4 ratio in early pregnancy and adverse neonatal outcomes: a retrospective cohort study.

Frontiers in endocrinology·2026
Same author

ALKBH4 confers ferroptosis resistance and drives tumorigenesis via dysregulation of GPX4 in breast cancer cells.

In vitro cellular & developmental biology. Animal·2026
Same author

Hydrodynamically Controlled Active Escape Dynamics.

Physical review letters·2026
Same author

Anomalous Transport of Elongated Particles in Oscillatory Vortical Flows.

Physical review letters·2026
Same author

Osmotic pressure regulates DNA labelling and transcription with dCas9-SunTag system in live cells.

Nature communications·2025

Related Experiment Video

Updated: Jun 24, 2025

Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series
07:59

Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series

Published on: May 10, 2020

7.7K

Multiflagellate Swimming Controlled by Hydrodynamic Interactions.

Shiyuan Hu1, Fanlong Meng1,2,3

  • 1CAS Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100190, China.

Physical Review Letters
|June 3, 2024
PubMed
Summary
This summary is machine-generated.

This study models multiflagellate microorganisms, revealing how flagellar interactions and configurations impact swimming efficiency. Optimal designs for microswimmers depend on flagellar arrangement and coordination.

More Related Videos

Biophysical Characterization of Flagellar Motor Functions
06:08

Biophysical Characterization of Flagellar Motor Functions

Published on: January 18, 2017

8.2K
Chemotactic Response of Marine Micro-Organisms to Micro-Scale Nutrient Layers
22:38

Chemotactic Response of Marine Micro-Organisms to Micro-Scale Nutrient Layers

Published on: May 28, 2007

13.4K

Related Experiment Videos

Last Updated: Jun 24, 2025

Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series
07:59

Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series

Published on: May 10, 2020

7.7K
Biophysical Characterization of Flagellar Motor Functions
06:08

Biophysical Characterization of Flagellar Motor Functions

Published on: January 18, 2017

8.2K
Chemotactic Response of Marine Micro-Organisms to Micro-Scale Nutrient Layers
22:38

Chemotactic Response of Marine Micro-Organisms to Micro-Scale Nutrient Layers

Published on: May 28, 2007

13.4K

Area of Science:

  • Biophysics
  • Fluid dynamics
  • Microbiology

Background:

  • Many eukaryotic microorganisms utilize multiple flagella for locomotion.
  • Understanding the complex hydrodynamics of multiflagellate swimmers is crucial for biological and engineering applications.

Purpose of the Study:

  • To model a three-dimensional multiflagellate swimmer and investigate the effects of flagellar actuation and configuration on swimming efficiency.
  • To explore the role of hydrodynamic interactions (HIs) and flagellar-body interactions in microswimmer locomotion.

Main Methods:

  • Development of a 3D computational model for a multiflagellate swimmer.
  • Simulation of synchronous and asynchronous flagellar actuation modes.
  • Analysis of flagellar-body interactions for different flagellar configurations (anterior vs. posterior).

Main Results:

  • Synchronous flagellar actuation efficiency is sensitive to flagellar tilting angles due to hydrodynamic interactions.
  • Asynchronous gaits can mitigate oscillatory motion through basal mechanical coupling.
  • Anterior flagellar configuration is advantageous over posterior configuration, which exhibits an optimal flagellar number.

Conclusions:

  • Hydrodynamic interactions significantly influence the swimming performance of multiflagellate microorganisms.
  • The findings provide insights into the locomotion strategies of microalgae and can inform the design of artificial microswimmers.