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A new lignan from Laggera crispata (Vahl) Hepper & J. R. I. Wood
Ming-Ming Tian1, Xiao-Li Chen1, Ji-Chun Wu1
1College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Natural Product Research
|June 3, 2024
Abstract:
A new lignan, 9'-O-angelyllariciresinol (1), and 20 known compounds (2-21) were isolated from the petroleum ether fraction of Laggera crispata (Vahl) Hepper & J. R. I. Wood. Their structures were identified by spectral analysis (NMR, IR, UV, and MS). Activity screening showed that compound 5 exhibited significant inhibitory effect on Staphylococcus aureus, while compound 2 exhibited significant inhibitory effect against liver cancer cell line HepG2.
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