Related Experiment Video

Updated: Jun 24, 2025

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
06:38

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Published on: March 11, 2016

12.0K

A Randomized Controlled Clinical Trial Testing Effects of Lademirsen on Kidney Function Decline in Adults with Alport

Daniel P Gale1,2,3, Oliver Gross4, Fang Wang5

  • 1Department of Renal Medicine, University College London, London, United Kingdom.

Clinical Journal of the American Society of Nephrology : CJASN
|June 3, 2024
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Assessment of Kidney Function in Mouse Models of Glomerular Disease
09:16

Assessment of Kidney Function in Mouse Models of Glomerular Disease

Published on: June 30, 2018

17.6K
Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

3.2K

Related Experiment Videos

Last Updated: Jun 24, 2025

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
06:38

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Published on: March 11, 2016

12.0K
Assessment of Kidney Function in Mouse Models of Glomerular Disease
09:16

Assessment of Kidney Function in Mouse Models of Glomerular Disease

Published on: June 30, 2018

17.6K
Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

3.2K

Related Concept Videos

Factors Affecting Renal Clearance: Renal Impairment01:17

Factors Affecting Renal Clearance: Renal Impairment

84
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
84
Renal Failure: Dose Adjustments01:11

Renal Failure: Dose Adjustments

84
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
84

Articles linked to this work by shared authors, journal, and citation graph.

Renal and systemic complications in autosomal dominant hypocalcemia type 1: a case series from North East England.

Journal of the Endocrine Society·2026

Finerenone Added to Renin-Angiotensin System- and Sodium-Glucose Cotransporter 2 Inhibition in Patients with Alport Syndrome: A Two-Center Case Series.

Kidney360·2026

Urine albumin-to-creatinine ratio as a predictor of kidney function decline in Alport syndrome.

Clinical kidney journal·2026

Anti-Glomerular Basement Membrane Nephritis Post-Renal Transplant in Alport Syndrome Patients.

Kidney360·2026

Albuminuria drives hyperlipidemia in patients with Alport syndrome.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026

Aggressive Natural Killer Cell Leukemia: A Rare and Rapidly Progressive Hematologic Malignancy-Case Report and Literature Review.

Case reports in hematology·2026

Comparative Renal Effectiveness of GLP-1RA and SGLT2i in US Veterans with Type 2 Diabetes and CKD.

Clinical journal of the American Society of Nephrology : CJASN·2026

Physical Performance and Risk of Heart Failure, Kidney Failure, and Mortality in CKD: Findings from the CRIC Study.

Clinical journal of the American Society of Nephrology : CJASN·2026

Integrated Risk Prediction of Kidney Failure: Clinical and Multi-Omic Approaches.

Clinical journal of the American Society of Nephrology : CJASN·2026

Association between Glycemic Control and Survival in Patients with Type 2 Diabetes on Peritoneal Dialysis: Results from the PDOPPS.

Clinical journal of the American Society of Nephrology : CJASN·2026

Early Changes in Kidney Transplantation following Implementation of the Increasing Organ Transplant Access Model.

Clinical journal of the American Society of Nephrology : CJASN·2026

A Mixed-Methods Study of How Older Adults with Advanced CKD Perceive Kidney Failure Risk.

Clinical journal of the American Society of Nephrology : CJASN·2026

Risk of malignant transformation in oral lichen planus and oral lichen planus with dysplasia: A retrospective clinical study of 435 histologically verified cases.

Dental and medical problems·2026

Routine abdominal drainage versus no drainage after elective hepatectomy: A systematic review and meta-analysis.

The Medical journal of Malaysia·2026

Liver Transplantation Versus Resection for Single-Nodule Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.

Journal of hepato-biliary-pancreatic sciences·2026

Cholecystocolonic Fistula With Acute Cholangitis: A Case Report.

Cureus·2026

Effects of Timing of Everolimus Transition on Renal Outcomes in Liver Transplant Recipients.

Journal of transplantation·2026

Intermittent Pneumatic Compression in Patients with Postmastectomy Lymphedema: A Randomized Controlled Trial.

Mymensingh medical journal : MMJ·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us