Related Experiment Video

Updated: Jun 24, 2025

Studying Mitotic Checkpoint by Illustrating Dynamic Kinetochore Protein Behavior and Chromosome Motion in Living Drosophila Syncytial Embryos
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Conserved signalling functions for Mps1, Mad1 and Mad2 in the Cryptococcus neoformans spindle checkpoint

Koly Aktar1, Thomas Davies1, Ioanna Leontiou1

  • 1Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

Plos Genetics
|June 3, 2024
PubMed
Summary

The spindle assembly checkpoint (SAC) in Cryptococcus neoformans is conserved, with Mps1 kinase and Mad1/Mad2 proteins ensuring accurate chromosome segregation during cell division.

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