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Updated: Jun 24, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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Structure-based identification of a G protein-biased allosteric modulator of cannabinoid receptor CB1

Siyuan Shen1,2, Chao Wu1, Guifeng Lin1

  • 1Division of Nephrology and Kidney Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.

Proceedings of the National Academy of Sciences of the United States of America
|June 3, 2024
PubMed

Keywords:
GPCRago-BAMscannabinoid receptor CB1nonopioid analgesicspain management

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