Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Action Potential01:31

Action Potential

7.9K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they...
7.9K
Action Potential: Phases of Stimulation01:28

Action Potential: Phases of Stimulation

5.4K
The action potential is a complex electrical event that occurs in excitable cells, such as neurons and muscle cells. It consists of several distinct phases, each with specific characteristics.
Resting Phase:
In this phase, the cell's membrane is at its resting potential, typically around -70 millivolts (mV) for neurons. Inside the cell, there is a higher concentration of potassium ions (K+) and a lower concentration of sodium ions (Na+). Voltage-gated sodium channels are closed, and...
5.4K
Action Potentials01:41

Action Potentials

130.6K
Overview
130.6K
Propagation of Action Potentials01:23

Propagation of Action Potentials

5.6K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
5.6K
Graded Potential01:19

Graded Potential

3.8K
Graded potentials are localized fluctuations in the cell membrane's electrical charge, commonly found in the dendrites of neurons. The magnitude of these potential changes depends on the strength of the initiating stimulus. In a membrane at its resting potential, a graded potential signifies a voltage shift either above -70 mV or below -70 mV.
Graded potentials fall into two categories: depolarizing and hyperpolarizing. Depolarizing graded potentials typically occur when sodium (Na+) or...
3.8K
Cardiac Action Potential01:30

Cardiac Action Potential

1.3K
Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The activity and expression of adenylosuccinate lyase were reduced during modern human evolution, affecting brain and behavior.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Value-related learning in the olfactory bulb occurs through pathway-dependent perisomatic inhibition of mitral cells.

PLoS biology·2024
Same author

State-dependent representations of mixtures by the olfactory bulb.

eLife·2022
Same author

Generation and Characterization of a Cell Type-Specific, Inducible Cre-Driver Line to Study Olfactory Processing.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2021
Same author

Fast odour dynamics are encoded in the olfactory system and guide behaviour.

Nature·2021
Same author

Rapid task-dependent tuning of the mouse olfactory bulb.

eLife·2019
Same journal

Brain-spleen axis regulates learned fear.

Nature reviews. Neuroscience·2026
Same journal

Acetylcholine: a candidate substrate for hippocampal predictive learning?

Nature reviews. Neuroscience·2026
Same journal

Astrocytes viewed through the lens of their proteomes and subproteomes.

Nature reviews. Neuroscience·2026
Same journal

m<sup>6</sup>A in RNA: a key regulator of brain development, function and disease.

Nature reviews. Neuroscience·2026
Same journal

Non-invasive deep-brain neuromodulation by transcranial radio frequency stimulation.

Nature reviews. Neuroscience·2026
Same journal

Heading into the wild: setting the course to natural neuroscience.

Nature reviews. Neuroscience·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2025

Subtype-specific Optical Action Potential Recordings in Human Induced Pluripotent Stem Cell-derived Ventricular Cardiomyocytes
06:59

Subtype-specific Optical Action Potential Recordings in Human Induced Pluripotent Stem Cell-derived Ventricular Cardiomyocytes

Published on: September 27, 2018

7.2K

Pattern recognition using action potential timing

Izumi Fukunaga1

  • 1Sensory and Behavioural Neuroscience Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan. izumi.fukunaga@oist.jp.

Nature Reviews. Neuroscience
|June 3, 2024
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
08:08

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

Published on: June 24, 2015

11.5K
Recording Single Neurons' Action Potentials from Freely Moving Pigeons Across Three Stages of Learning
11:20

Recording Single Neurons' Action Potentials from Freely Moving Pigeons Across Three Stages of Learning

Published on: June 2, 2014

12.0K

Related Experiment Videos

Last Updated: Jun 24, 2025

Subtype-specific Optical Action Potential Recordings in Human Induced Pluripotent Stem Cell-derived Ventricular Cardiomyocytes
06:59

Subtype-specific Optical Action Potential Recordings in Human Induced Pluripotent Stem Cell-derived Ventricular Cardiomyocytes

Published on: September 27, 2018

7.2K
Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
08:08

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

Published on: June 24, 2015

11.5K
Recording Single Neurons' Action Potentials from Freely Moving Pigeons Across Three Stages of Learning
11:20

Recording Single Neurons' Action Potentials from Freely Moving Pigeons Across Three Stages of Learning

Published on: June 2, 2014

12.0K