Association between hypertension and osteoporosis: a population-based cross-sectional study

Area of Science:

• Cardiovascular Health
• Bone Metabolism
• Epidemiology

Background:

• Metabolic dysregulation is associated with hypertension and osteoporosis.
• The direct correlation between hypertension and osteoporosis remains unclear.
• This study investigates the relationship between hypertension and osteoporosis.

Purpose of the Study:

• To explore the correlation between hypertension and osteoporosis.
• To assess the association between hypertension and osteoporosis in a large population-based sample.

Main Methods:

• Utilized data from 37,807 participants in the National Health and Nutrition Examination Survey (NHANES).
• Employed logistic regression and subgroup analysis to examine the association.
• Hypertension was treated as the exposure, and osteoporosis as the outcome.

Main Results:

• Participants with osteoporosis had a higher prevalence of hypertension (p < 0.001).
• Hypertension was independently associated with osteoporosis (aOR: 1.183, p = 0.004).
• Significant associations were observed in subgroups: <60 years, males, diabetes, and hypercholesterolemia.

Conclusions:

• Hypertension is independently associated with osteoporosis in the general population.
• The findings suggest a link between hypertension and increased osteoporosis risk.
• Further research may elucidate underlying mechanisms and clinical implications.