[Antimicrobial therapy]

The Authors expose the bases of a rational antibiotic therapy according to their experience. They underline the risk of using antibiotics in situations in which they are not strictly necessary. They point out the importance of the dosage, the route of administration, the frequency of doses, the length of treatment and the control of seric drug levels of aminoglycosides, in case of creatinine clearance under 50 ml/min. They shortly review the different antibiotic combination.