Clinical characteristics and predictors of in-hospital mortality of patients hospitalized with myocardial infarction...

Area of Science:

• Cardiology
• Public Health
• Epidemiology

Background:

• The COVID-19 pandemic significantly disrupted healthcare, including the management of acute coronary syndrome (ACS).
• Assessing the impact on ACS patient profiles and outcomes is crucial for understanding pandemic-related healthcare challenges.

Purpose of the Study:

• To compare patient demographics, ACS characteristics, and in-hospital outcomes before and during the COVID-19 pandemic.
• To evaluate changes in ACS admission rates and treatment strategies during the pandemic.

Main Methods:

• Retrospective analysis of 1209 patients admitted with ACS.
• Comparison of clinical, demographic, comorbidity, laboratory, and periprocedural data between pre-pandemic (March 2019-February 2020) and pandemic (March 2020-February 2021) periods.
• Assessment of in-hospital mortality and its relationship with patient and disease characteristics.

Main Results:

• A 17.8% decrease in ACS admissions was observed during the pandemic.
• STEMI (ST-elevation myocardial infarction) admissions increased, while conservative treatment decreased.
• Despite changes in patient profiles and treatment, in-hospital all-cause and cardiac death rates remained similar between the two periods.

Conclusions:

• The COVID-19 pandemic led to a reduction in ACS admissions but did not significantly alter in-hospital mortality rates.
• Healthcare systems maintained comparable outcomes for ACS patients despite pandemic-induced changes in patient presentation and treatment patterns.