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Updated: Jun 24, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
Published on: July 27, 2021
Genetic association mapping leveraging Gaussian processes
1Division of Digital Genomics, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan. kumasaka@hgc.jp.
Abstract:
Gaussian processes (GPs) are a powerful and useful approach for modelling nonlinear phenomena in various scientific fields, including genomics and genetics. This review focuses on the application of GPs in genetic association mapping. The aim is to identify genetic variants that alter gene regulation along continuous cellular states at the molecular level, as well as disease susceptibility over time and space at the population level. The challenges and opportunities in this field are also addressed.
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