Related Experiment Video
Updated: May 10, 2026
Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Hybrid versus traditional method closure of ventricular septal defects in children
Akkerbez Adilbekova1,2, Shukhrat Marassulov1, Abay Baigenzhin1
1Department of Pediatric Cardiac Surgery, National Scientific Medical Center, Astana City, Republic of Kazakhstan.
Insights
The hybrid off-pump method for ventricular septal defect (VSD) closure is safe and effective in children, offering shorter operation times and improved cosmetics compared to the traditional on-pump technique.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
Background:
- Isolated ventricular septal defect (VSD) is a common congenital heart anomaly.
- Surgical closure is the standard treatment for VSD.
- Traditional VSD closure utilizes an on-pump cardiopulmonary bypass method.
Purpose of the Study:
- To evaluate the safety and effectiveness of a hybrid off-pump method for VSD closure.
- To compare the hybrid off-pump method with the traditional on-pump method in pediatric patients.
Main Methods:
- Retrospective cohort study.
- Involved 500 pediatric patients with isolated VSD undergoing surgery between May 2016 and December 2020.
- Compared outcomes between the hybrid off-pump (n=250) and traditional on-pump (n=250) VSD closure methods.
Main Results:
- The hybrid off-pump method achieved a 93.2% procedural success rate with a 6.4% conversion rate.
- Mean operation time was significantly shorter for the hybrid group (84 minutes) versus the traditional group (168 minutes) (P=.000).
- Hospital mortality was lower in the hybrid group (0.43%) compared to the traditional group (1.5%) (P=.000).
Conclusions:
- The hybrid off-pump VSD closure is a safe and effective option for select pediatric patients.
- Advantages include improved cosmetic outcomes and reduced operation time.
- Shorter overall hospital stay is also a benefit of the hybrid approach.
Objective:
The aim of our study was to evaluate the safety and effectiveness of the hybrid method off-pump for closure of isolated ventricular septal defect (VSD) compared with the traditional method of on-pump of children.
Methods:
This research was a retrospective cohort study. Data were collected from 500 patients with isolated VSD (or residual VSD after a previous repair) who underwent surgery at the National Scientific Medical Center from May 2016 to December 2020. Patients were operated with 1 of 2 methods of surgery: the traditional method of on-pump or the hybrid method of off-pump. This study assessed the safety and efficacy of the hybrid method by comparing it with the traditional method for the treatment of patients with isolated VSD.
Results:
The procedural success rate reached 93.2% in the hybrid method, with a 6.4% conversion rate to the traditional method and 0.4% hospital mortality. The mean operation time was 84 minutes (31; 160 minutes) in the hybrid group (n = 250) and 168 minutes (70; 300 minutes) in the traditional group (n = 250) (P = .000). Hospital mortality was 0.43% in the first group and 1.5% in the second group (P = .000).
Conclusions:
The hybrid method of VSD closure is safe and effective in a selected group of patients. The advantages of the hybrid method are improved cosmetics and shorter operation time and overall hospital stay.
