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Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
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Updated: Jun 24, 2025

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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Colorectal cancer: Getting the perspective and context right.

Jun De Lu1, Kok Yang Tan2

  • 1Department of General Surgery, Khoo Teck Puat Hospital, Singapore 768828, Singapore.

World Journal of Clinical Oncology
|June 5, 2024
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Colorectal cancer (CRC) is a major global health issue, particularly in developed nations. This review focuses on managing CRC in elderly patients, considering their complex physiology and care goals.

Keywords:
Cancer epidemiologyColorectal cancerHolistic careManagementScreening

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Area of Science:

  • Oncology
  • Geriatric Medicine
  • Public Health

Background:

  • Colorectal cancer (CRC) ranks as the third leading cancer globally, with higher incidence in North America and Europe.
  • Geographical variations in CRC mortality rates highlight the need for targeted public health interventions.
  • An increasing and aging global population predicts a rise in CRC cases, complicating patient management.

Discussion:

  • Effective CRC management necessitates understanding its pathophysiology and the interplay with patient physiology.
  • Early detection through screening and tailored treatment strategies are crucial for improving patient outcomes.
  • Healthcare professionals must navigate complex patient factors, including age and comorbidities, when developing CRC treatment plans.

Key Insights:

  • The aging population presents unique challenges in CRC diagnosis and treatment.
  • Personalized treatment approaches considering geriatric-specific factors are essential for optimal CRC care.
  • A comprehensive understanding of CRC pathophysiology is vital for managing complex elderly patients.

Outlook:

  • Future research should focus on optimizing CRC screening and treatment protocols for the elderly population.
  • Developing evidence-based guidelines for geriatric CRC management is a priority.
  • Advancements in understanding CRC biology may lead to more effective, age-specific therapies.