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  1. Home
  2. Recent Trends In The Incidence Of Early-onset Prostate Cancer.
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  2. Recent Trends In The Incidence Of Early-onset Prostate Cancer.

Related Experiment Video

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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Recent trends in the incidence of early-onset prostate cancer.

Yanjun Zheng1, Jinshui Mao1, Lina Yang2

  • 1Department of Urology, Quzhou Hospital of Traditional Chinese Medicine, Quzhou.

European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)
|June 5, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Early-onset prostate cancer (EOPC) incidence increased then sharply declined, with non-Hispanic Black men showing the highest rates. Declining EOPC trends highlight the need for targeted screening, especially for Black youth.

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Area of Science:

  • Oncology
  • Epidemiology
  • Public Health

Background:

  • Early-onset prostate cancer (EOPC) is uncommon, and its evolving incidence trends are not well-understood.
  • Prostate cancer in younger men presents unique challenges and requires specific epidemiological investigation.

Purpose of the Study:

  • To analyze trends in the incidence, stage at diagnosis, race/ethnicity, and treatment patterns of EOPC.
  • To identify disparities and inform targeted public health interventions for EOPC.

Main Methods:

  • Utilized the Surveillance, Epidemiology, and End Results (SEER) database from 2000 to 2020.
  • Analyzed prostate cancer cases in men under 55 years, focusing on annual age-adjusted incidence rates (AAIR) and treatment modalities.

Main Results:

  • EOPC incidence showed a wave-like increase from 2000-2007, followed by a sharp decline to 2014 and further decrease by 2020.
  • Non-Hispanic Black men consistently had the highest EOPC incidence with the slowest reduction rate.
  • The proportion of patients receiving prostatectomy decreased significantly from 2010 to 2020.

Conclusions:

  • Declining EOPC rates across racial groups necessitate focused research and interventions.
  • There is an urgent need for tailored prostate cancer screening protocols, particularly for Black youth.