Related Experiment Video
Updated: Jun 24, 2025

In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy
Published on: December 9, 2015
Incidentally Discovered 99mTc-MDP Uptake on Bone Scan in Otosclerosis
Karl Berendt1, Ho Jen1, Richard Liu2
1Faculty of Medicine and Dentistry, Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
Otosclerosis, a cause of hearing loss, can now be detected using bone scans. This nuclear medicine imaging technique shows 99mTc-MDP uptake, offering new ways to diagnose and manage the condition.
Area of Science:
- Otolaryngology
- Nuclear Medicine
- Radiology
Background:
- Otosclerosis is a poorly understood condition causing progressive conductive hearing loss.
- Current diagnostic methods for otosclerosis have limitations.
Observation:
- This study presents the first evidence of otosclerosis demonstrating 99mTc-MDP uptake on bone scan.
- This uptake indicates active bone remodeling in affected areas.
Findings:
- 99mTc-MDP uptake on bone scan is a novel imaging biomarker for otosclerosis.
- This finding suggests nuclear medicine can visualize otosclerotic activity.
Implications:
- Nuclear medicine imaging may aid in the early detection and staging of otosclerosis.
- This approach could inform treatment strategies and prognosis assessment for patients with hearing loss.
More Related Videos
06:31Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain
Published on: August 8, 2019
06:59Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
Published on: September 8, 2023