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Boronyl-Group-Assisted Decatungstate-Catalyzed Benzylic C(sp3)-H Alkylation
Hui Jiang1, Takeru Torigoe2, Yoichiro Kuninobu1,3
1Department of Interdisciplinary Engineering Sciences, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, 6-1 Kasugakoen, Kasuga-shi, Fukuoka 816-8580, Japan.
Abstract:
Boronic acid synthesis primarily involves the introduction of boronyl groups. However, an alternative route that involves the functionalization of boronic acids has not received much attention. This study describes the catalytic C(sp3)-H alkylation of ortho-tolylboronic acids utilizing the interaction between a free boronyl group [-B(OH)2] and a decatungstate photocatalyst [W10O32]4-. The boronyl groups of the alkylated products could be converted without isolation of the alkylated product.
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