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Updated: Jun 24, 2025

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Plasma levels of complement components C5 and C9 are associated with thrombin generation

Rocío Vacik Díaz1, Gaëlle Munsch2, Maria Jesus Iglesias3

  • 1Cardiovascular and Nutrition Research Center Centre de recherche en CardioVasculaire et Nutrition (C2VN), Aix-Marseille University, Institut national de la santé et de la recherche médicale 1263, Institut national de recherche pour l'agriculture, l'alimentation et l'environnement 1260, Marseille, France; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg, Mainz, Germany. Electronic address: https://twitter.com/RocioVacik.

Journal of Thrombosis and Haemostasis : JTH
|June 5, 2024
PubMed
Summary

Complement proteins C5 and C9 were identified as novel determinants of thrombin generation. This multiomics study provides insights into hemostatic balance and cardiovascular risk factors.

Keywords:
complement C5complement C9proteomicsthrombinvenous thromboembolism

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