Related Experiment Video
Updated: Jun 24, 2025
A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Effectiveness of self-management programmes for heart failure with reduced ejection fraction: a systematic review
Pupalan Iyngkaran1,2, Monika Buhler3, Maximilian de Courten4
1NT Medical School, The University of Notre Dame Australia Melbourne Clinical School, Werribee, Victoria, Australia.
Insights
This systematic review examines chronic disease self-management (CDSM) programs for congestive heart failure (CHF) patients. It synthesizes evidence to determine CDSM effectiveness and impact on major adverse cardiovascular events (MACE).
Area of Science:
- Cardiology and Cardiovascular Diseases
- Health Services Research
- Evidence-Based Medicine
Background:
- Chronic disease self-management (CDSM) is crucial for congestive heart failure (CHF) care.
- Recent guidelines question the evidence for CDSM programs in CHF.
- A comprehensive review is needed to assess CDSM effectiveness in CHF.
Purpose of the Study:
- To systematically review and synthesize evidence on CDSM programs for CHF patients.
- To determine the effectiveness of CDSM interventions on major adverse cardiovascular events (MACE).
Main Methods:
- Systematic review of randomized controlled trials from 1966 to 2024 across multiple databases.
- Inclusion of studies on CDSM and CHF with reported MACE; data extraction and quality appraisal by two independent reviewers.
- Quantitative synthesis and meta-analysis (if feasible) to assess the primary outcome of MACE changes.
Main Results:
- The review protocol is established, adhering to PRISMA guidelines.
- Data extraction and analysis will focus on MACE as the primary outcome.
- Subgroup analyses will explore variations across different CDSM program types.
Conclusions:
- This systematic review will provide synthesized evidence on CDSM effectiveness in CHF.
- Findings will inform clinical practice and guideline development regarding CDSM for CHF.
- Dissemination through peer-reviewed journals and conferences is planned.
Introduction:
Chronic disease self-management (CDSM) is a vital component of congestive heart failure (CHF) programmes. Recent CHF guidelines have downgraded CDSM programmes citing a lack of gold-standard evidence. This protocol describes the aims and methods of a systematic review to collate and synthesise the published research evidence to determine the effectiveness of CDSM programmes and interventions for patients treated for CHF.
Methods:
Medline, PubMed, Embase, CENTRAL, CINAHL, Cochrane Central Register of Controlled Trials, PsycINFO, SCOPUS, Web of Science, the Science Citation Index and registers of clinical trials will be searched from 1966 to 2024. In addition, the reference lists of shortlisted articles will be reviewed. Randomised controlled trials, with case management interventions of CDSM and CHF with reported major adverse cardiovascular events (MACEs), will be extracted and analysed. There is no restriction on language. Study protocol template developed from Cochrane Collaboration and Reporting adheres to Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocol guidelines for systematic review and meta-analyses 2020. Two independent authors will apply inclusions and exclusion criteria to limit article search and assess bias and certainty of evidence rating. Data extraction and study description of included studies will include quality appraisal of studies and quantitative synthesis of data will then be undertaken to ascertain evidence for the study aims. Subgroup analyses will be conducted for different CDSM programmes. The primary outcome will be a significant change in MACE parameters between intervention and control arms. Meta-analysis will be conducted using statistical software, if feasible.
Ethics And Dissemination:
Ethics approval is not sought as the study is not collecting primary patient data. The results of this study will be disseminated through peer-reviewed scientific journals and also presented to audiences through meetings and scientific conferences.
Prospero Registration Number:
CRD42023431539.
Related Concept Videos
01:26Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
01:17Pathophysiology of Heart Failure
01:22Heart Failure Drugs: β-Blockers
01:22Heart Failure Drugs: Diuretics
01:26Stress Prevention and Stress Management Techniques I
Conscientiousness
Conscientious individuals tend to be organized, responsible, and disciplined. They prioritize completing tasks and following structured routines,...
01:30Stress Prevention and Stress Management Techniques VI
Motivation and Self-Determination
Motivation, the driving force behind behavior, plays a pivotal role at every stage of the change process. The research...