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Published on: September 5, 2017
Factors Associated With Extrapulmonary Tuberculosis in Southeastern Mexico: A Case-Control Study.
Jorge Fernando Luna-Hernández1, María Del Pilar Ramírez-Díaz1, Abel Eduardo Zavala2
1Biological and Health Sciences, University of the Isthmus, Juchitán, MEX.
Extrapulmonary tuberculosis (EPTB) is more common in younger women, indigenous populations, and those in urban areas. Factors like HIV/AIDS, adenopathy, and dyspnea increase EPTB risk, aiding early diagnosis and prevention.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Extrapulmonary tuberculosis (EPTB) affects any organ and poses diagnostic challenges.
- Increased clinical awareness is vital due to severe sequelae and diagnostic barriers.
Purpose of the Study:
- To identify factors associated with EPTB in Oaxaca, Mexico.
- To improve early detection and prevention strategies for EPTB.
Main Methods:
- Unpaired case-control study comparing EPTB+ cases with pulmonary tuberculosis (PTB+) controls.
- Sociodemographic, clinical, and microbiological data were collected.
- Logistic regression analysis was used to determine odds ratios (OR).
Main Results:
- 75 EPTB+ cases and 300 PTB+ controls were analyzed.
- Age <40 years, female sex, urban residence, and HIV/AIDS comorbidity were associated with EPTB.
- Clinical signs like dyspnea and adenopathy were also positively associated with EPTB.
Conclusions:
- Findings support targeted screening for EPTB, focusing on high-risk groups.
- Identifying women under 40, HIV/AIDS patients, and urban residents can enhance EPTB prevention.
- Presence of adenopathy and dyspnea are key clinical indicators for EPTB screening.
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