Novel Anatomical Variation of Left Coronary Artery Origin at the Sinotubular Junction Level With Coeval Hypoplastic
Parishmita Barman1, Andrew John2
1Department of Radiology, Sree Balaji Medical College & Hospital, Chennai, IND.
Cureus
|June 6, 2024
Summary
This case report details a rare combination of left coronary artery anomalies and coronary artery disease in a 37-year-old male. It highlights the importance of advanced imaging for diagnosing complex coronary artery anatomy.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Congenital anomalies of the coronary arteries, such as isolated left coronary artery (LCA) ostium origin at the sinotubular junction (STJ) and congenital absence of the left circumflex (LCx) coronary artery, are documented.
- Superdominant right coronary artery (SRCA) circulation has been observed with absent LCx, but its association with a hypoplastic LCx (HLCx) is less understood.
Observation:
- A 37-year-old male with diabetes and hypertension presented with syncope during exercise.
- He had an anomalous LCA origin at the STJ, HLCx, and SRCA, alongside mild to moderate coronary artery disease affecting the LAD, LCx, and RCA.
Findings:
- This report is the first to describe the combined association of STJ LCA origin, HLCx, SRCA, and coronary artery disease.
- The presented case also suggests a potential risk of malignancy.
Implications:
- Computed tomography angiography (CTA) is recommended over conventional coronary angiography for diagnosing complex coronary artery anomalies to prevent adverse outcomes.
- Accurate knowledge of coronary artery anatomy and pathology is crucial for interventional cardiologists, cardiothoracic surgeons, and radiologists to ensure safe and effective coronary interventions.
Keywords:
computed tomography coronary angiographycoronary artery angiographycoronary artery anomalies originhypoplasialeft anterior descending arteryleft circumflex artery (lcx)left main coronary artery disease (lmcad)right coronary artery (rca)sinotubular junctionMore Related Videos
10:39Murine Left Anterior Descending LAD Coronary Artery Ligation: An Improved and Simplified Model for Myocardial Infarction
Published on: April 2, 2017
24.6K
13:10Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
Published on: April 24, 2017
18.5K
Related Concept Videos
01:21Coronary Circulation
The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
01:10The Arch of Aorta
The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
Encircling the heart, the coronary arteries form a ring-like structure before...
01:24Cardiac Catheterization III: Left Heart Catheterization
Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
01:30Coronary Artery Disease I: Introduction
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
01:26Coronary Artery Disease II: Pathophysiology
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
01:30Coronary Artery Disease III: Clinical Manifestations
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...