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Descending Colon Metastasis of Renal Cell Carcinoma: An Unusual Site of Metastasis

  • 0Internal Medicine, HCA Florida Northwest Hospital, Margate, USA.
Cureus +

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June 6, 2024

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June 6, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

This case report details an uncommon instance of metastatic renal cell carcinoma (RCC) to the descending colon. The findings highlight the importance of considering rare metastatic sites in patients with a history of RCC.

Area Of Science

  • Oncology
  • Gastroenterology

Background

  • Renal cell carcinoma (RCC) frequently metastasizes, typically to lungs, liver, bone, and brain.
  • Gastrointestinal metastasis from RCC is rare, with most cases involving the small bowel or stomach.

Observation

  • An 87-year-old male with a history of stage III RCC presented with melena and abdominal pain.
  • Imaging revealed a colonic mass in the descending colon, confirmed as metastatic RCC via biopsy.

Findings

  • The colonic mass showed atypical cells positive for PAX8, CD10, and cytokeratin, consistent with metastatic RCC.
  • The tumor was negative for CDX2, TTF-1, and CD68, ruling out primary colorectal, lung, or other origins.

Implications

  • This case underscores the possibility of rare colonic metastasis from renal cell carcinoma.
  • Highlights the need for comprehensive diagnostic evaluation in patients with a history of RCC presenting with gastrointestinal symptoms.

Keywords: