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Related Concept Videos

Blind Procedures02:07

Blind Procedures

Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which child was...
Blinding01:11

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

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Single-session associative protocol for dentin hypersensitivity management: a 1-year randomized, blinded clinical

Thayna Carolina Zeni1, Poliana Maria de Faveri Cardoso1, Rafael da Silva Vanolli1

  • 1Department of Restorative Dentistry, School of Dentistry, Western State University of Paraná, Cascavel, PR, Brazil.

Restorative Dentistry & Endodontics
|June 6, 2024
PubMed
Summary

This study evaluated single-session treatments for dentin hypersensitivity (DH). All tested protocols effectively managed DH for up to 12 months, with significant results observed in the control and Remineralizing Desensitizing Protocol (PDR) groups.

Keywords:
Clinical trialDental researchDentin hypersensitivityQuality of life

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Area of Science:

  • Dentistry
  • Dental Materials Science
  • Clinical Research

Background:

  • Dentin hypersensitivity (DH) is a common clinical condition.
  • Non-restorative management aims to alleviate DH symptoms without invasive procedures.
  • Single-session protocols offer a convenient treatment approach.

Purpose of the Study:

  • To establish and evaluate a single-session associative protocol for non-restorative management of dentin hypersensitivity (DH).
  • To compare the efficacy of different desensitizing agents over a 12-month period.

Main Methods:

  • A split-mouth study involving 24 individuals with DH (minimum VAS score of 4).
  • Four treatment groups were assessed: control (universal adhesive), Neural Desensitizing Protocol (5% potassium nitrate), Mixed Desensitizing Protocol (PAM: 5% sodium fluoride and 5% potassium nitrate), and Remineralizing Desensitizing Protocol (PDR: surface-partially reacted glass technology photopolymerizable varnish).
  • Visual analog scale (VAS) sensitivity tests were conducted immediately post-application and at 1 week, 1 month, 2 months, and 12 months.

Main Results:

  • All treatment groups demonstrated statistically significant reductions in DH scores compared to baseline at the 12-month evaluation.
  • Significant differences were found between the PAM group, control group, and PDR group at 12 months.
  • The control group and PDR group showed particularly significant results.

Conclusions:

  • All evaluated single-session desensitizing protocols are effective in managing dentin hypersensitivity.
  • The control group and the Remineralizing Desensitizing Protocol (PDR) group yielded significant long-term results.
  • Single-session desensitizing protocols can provide effective DH control for up to 12 months.