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Analysis of the pharmacokinetics and efficacy of RBD1016 - A GalNAc-siRNA targeting Hepatitis B Virus X gene using

Qian Li1, Taohua Geng2, Haiyan Li2

  • 1Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Heliyon
|June 6, 2024
PubMed

Keywords:
GalNAcHepatitis B virusN-acetyl galactosaminePharmacokineticSemi-mechanistic modelSmall interference RNAsiRNA

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