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Robotic Pills as Innovative Personalized Medicine Tools: A Mini Review.

Komal Rane1, Garima Kukreja1, Siddhi Deshmukh1

  • 1Department of Pharmacy Practice, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune - 411018, Maharashtra, India.

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Summary

Robotic pills offer a novel solution to overcome challenges in oral drug delivery, enhancing drug absorption and enabling targeted delivery. This technology also shows potential for diagnosis and drug dispensing within the gastrointestinal tract.

Keywords:
GI tractRobotic pillbiologicsnon-invasivenessoral deliveryrheumatoid arthritis.

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Area of Science:

  • Pharmaceutical Technology
  • Drug Delivery Systems
  • Biomedical Engineering

Background:

  • Oral drug administration is preferred for its convenience but faces limitations in drug stability, permeability, and solubility.
  • Biologic drugs are particularly challenging for oral delivery due to their degradability, necessitating injections.
  • Existing novel drug delivery systems aim to improve oral absorption but have limitations.

Purpose of the Study:

  • To review recent advancements in robotic pill technology for oral drug delivery.
  • To explore the potential of robotic pills in overcoming gastrointestinal absorption challenges.
  • To discuss the applications of robotic pills in drug delivery, diagnosis, and dispensing.

Main Methods:

  • Review of current literature on robotic pill technology and drug delivery systems.
  • Analysis of the mechanisms by which robotic pills enhance drug adhesion and permeation.
  • Discussion of case studies and potential future applications.

Main Results:

  • Robotic pills demonstrate potential to significantly enhance drug adhesion and permeation through the GI mucus membrane.
  • This technology can facilitate targeted drug delivery to specific sites within the gastrointestinal tract.
  • Robotic pills offer potential for integrated diagnostic capabilities and automated drug dispensing.

Conclusions:

  • Robotic pills represent a promising innovation in pharmaceutical technology to address limitations of oral drug delivery.
  • The technology has the potential to improve the efficacy of oral medications, especially biologics.
  • Further development of robotic pill drug-device technology could revolutionize gastrointestinal drug delivery and diagnostics.