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Published on: November 10, 2017
[Modern Fixed Combinations in the Correction of Arterial Hypertension and Dyslipidemia]
Z M Galeeva1, A S Galyavich1, L V Baleeva1
1Kazan State Medical University.
Insights
This case report highlights the personalized treatment of arterial hypertension and dyslipidemia using a fixed-combination therapy. Equamer® (amlodipine, lisinopril, rosuvastatin) effectively addressed key cardiovascular disease risk factors.
Area of Science:
- Cardiology
- Pharmacology
- Internal Medicine
Background:
- Arterial hypertension and dyslipidemia are significant risk factors for cardiovascular diseases.
- Ischemic heart disease often coexists with arterial hypertension, necessitating targeted therapeutic strategies.
Purpose of the Study:
- To present a clinical case demonstrating the individual selection of effective therapy for a patient with arterial hypertension and dyslipidemia.
- To evaluate the appropriateness of a fixed triple combination therapy in managing combined cardiovascular risk factors.
Main Methods:
- A clinical case report approach was utilized.
- Therapeutic selection was based on patient-specific risk factors and clinical guidelines.
- Equamer® (amlodipine + lisinopril + rosuvastatin) was chosen as the fixed-combination therapy.
Main Results:
- The selected fixed triple combination therapy (amlodipine, lisinopril, rosuvastatin) was deemed highly appropriate for the patient's clinical profile.
- This combination effectively targets both arterial hypertension and dyslipidemia, major contributors to cardiovascular risk.
Conclusions:
- Individualized therapy selection is crucial for managing complex cardiovascular conditions.
- Fixed triple combination therapy, such as Equamer®, offers a rational approach to addressing multiple cardiovascular risk factors simultaneously.
Abstract:
Based on a clinical case report, the article shows the individual selection of effective therapy for a patient with arterial hypertension and dyslipidemia. Taking into account the risk factors for cardiovascular diseases, Equamer® was selected as a fixed combination of amlodipine + lisinopril + rosuvastatin capsules 10 mg+20 mg+10 mg (Gedeon Richter Plc, Budapest, Hungary). In the patient with hypertension, ischemic heart disease was verified, and stenting of the anterior descending artery was performed. According to the clinical guidelines, when arterial hypertension is associated with ischemic heart disease, the drug therapy of choice should be a combination of dihydropyridine slow calcium channel blockers with an angiotensin-converting enzyme inhibitor. The fixed triple combination of amlodipine, lisinopril, and rosuvastatin is one of the most appropriate in this clinical situation; this combination targets the two major risk factors for cardiovascular diseases, arterial hypertension and dyslipidemia.
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