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Published on: June 12, 2021
Cardiogenic shock trajectories: is the Society for Cardiovascular Angiography and Interventions definition the right
David Dorian1,2, Ross J Thomson1,3, Hoong Sern Lim4,5
1Barts Heart Centre, Barts Health NHS Trust, London, UK.
Insights
The Society for Cardiovascular Angiography and Interventions (SCAI) cardiogenic shock classification system needs evolution. Serial reassessment and advanced data integration, including AI, can improve prediction of shock trajectory and outcomes.
Area of Science:
- Cardiology
- Critical Care Medicine
- Medical Classification Systems
Background:
- The current Society for Cardiovascular Angiography and Interventions (SCAI) classification system is a key tool for assessing cardiogenic shock.
- Understanding cardiogenic shock trajectory is crucial for patient management and predicting outcomes.
Purpose of the Study:
- To review the existing SCAI cardiogenic shock classification system.
- To explore potential enhancements and alternative approaches for describing cardiogenic shock progression.
Main Methods:
- Review of current literature and existing SCAI classification guidelines.
- Analysis of studies investigating serial reassessment of SCAI stages.
- Examination of registry data and advanced assessment techniques (hemodynamics, imaging, labs).
- Consideration of machine learning and artificial intelligence for data integration.
Main Results:
- Serial reassessment of SCAI stages within 24 hours of shock onset shows prognostic value for predicting deterioration and outcomes.
- Precise assessment of macrocirculation and microcirculation using invasive hemodynamics, imaging, and other markers is beneficial.
- Machine learning and AI offer potential for integrating multimodal data into real-time metrics to define trajectory and guide therapy.
Conclusions:
- The SCAI staging system remains essential for cardiogenic shock assessment, communication, and reassessment.
- Evolving our methods for measuring and assessing shock trajectory is vital.
- Sophistication in assessing shock progression must parallel our understanding of its complexity and variability.
Purpose Of Review:
We review the current Society for Cardiovascular Angiography and Interventions (SCAI) cardiogenic shock classification system and consider alternatives or iterations that may enhance our current descriptions of cardiogenic shock trajectory.
Recent Findings:
Several studies have identified the potential prognostic value of serial SCAI stage re-assessment, usually within the first 24 h of shock onset, to predict deterioration and clinical outcomes across shock causes. In parallel, numerous registry-based analyses support the utility of a more precise assessment of the macrocirculation and microcirculation, leveraging invasive haemodynamics, imaging and additional laboratory and clinical markers. The emergence of machine learning and artificial intelligence capabilities offers the opportunity to integrate multimodal data into high fidelity, real-time metrics to more precisely define trajectory and inform our therapeutic decision making.
Summary:
Whilst the SCAI staging system remains a pivotal tool in cardiogenic shock assessment, communication and reassessment, it is vital that the sophistication with which we measure and assess shock trajectory evolves in parallel our understanding of the complexity and variability of clinical course and clinical outcomes.
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