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How to improve epidemiological trustworthiness concerning abdominal aortic aneurysms
Fabio Zecca1, Gavino Faa2, Roberto Sanfilippo3
1Department of Radiology, University Hospital "D. Casula", Cagliari, Italy.
Vascular
|June 6, 2024
Summary
Epidemiological data on abdominal aortic aneurysms (AAA) is unreliable due to inconsistencies. Standardizing measurements and adopting patient-tailored approaches can improve AAA diagnosis and management.
Area of Science:
- Vascular Surgery
- Epidemiology
- Medical Imaging
Background:
- Degenerative abdominal aortic aneurysms (AAA) research faces challenges from complex pathophysiology and inadequate models.
- Trustworthiness of existing AAA epidemiological data is compromised by ambiguity and inconsistency.
Purpose of the Study:
- To foster debate on the trustworthiness of AAA epidemiological data.
- To discuss potential solutions for improving AAA data reliability and patient care.
Main Methods:
- Literature search of the past five decades for AAA epidemiological data.
- Discussion of issues impacting AAA epidemiological figures.
- Proposal of suggestions for AAA diagnosis, prognostication, and management.
Main Results:
- AAA prevalence appears to be decreasing globally, but mortality is increasing.
- Prevalence and mortality trends differ between high-income and low-income countries.
- Current AAA definitions lack reliability due to ignoring inter-individual aortic size variability.
Conclusions:
- Shifting to relative aortic indices and standardizing aortometry will enhance AAA epidemiological trustworthiness.
- A patient-tailored approach integrating clinical data, indices, and imaging is desirable for AAA management.
- Novel imaging modalities, contrast agents, and AI show promise for AAA investigation.
