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Minimally Invasive Blood Collection for an Mpox Serosurvey among People Experiencing Homelessness
Caroline J Waddell1,2, Gerald J Pellegrini1, Neela Persad1
1Mpox Emergency Response, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Background:
People experiencing homelessness (PEH) are underrepresented in public health and clinical research. Study methods that can improve participation by this group are needed.
Methods:
In late 2022, the Centers for Disease Control and Prevention conducted an mpox serological survey using venipuncture among PEH in San Francisco, California. Blood collection by a minimally invasive device was offered if venipuncture was not possible or preferred. Participants who had a successful blood draw using the device were asked about device acceptability.
Results:
Of the 209 successful blood collections, 137 (66%) were among participants who underwent venipuncture and 72 (34%) were among participants who used the device. Use of the device increased overall blood collection participation by 53%. Participants reported high acceptability and preference for the device over venipuncture.
Conclusions:
Minimally invasive blood collection devices may increase participation and representation of PEH in serosurveys.
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