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Protein Complex Assembly

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types. Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...

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Related Experiment Video

Updated: Jun 24, 2025

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

On-demand modular assembly for expedited PROTAC development

Ayan Mukherjee^1,2, Vilas D Kadam^1,2, Qi Miao^1,2

¹Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.

Expert Opinion on Drug Discovery

|June 6, 2024

Summary

No abstract available in PubMed .

Keywords:

PROTAC click chemistry direct-to-biology library synthesis modular assembly parallel synthesis split linker

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