Disulfide Bonds as Functional Tethers in Metal-Organic Frameworks.

Area of Science:

• Materials Science
• Chemistry
• Nanotechnology

Background:

• Metal-organic frameworks (MOFs) are advanced porous materials with tunable properties.
• Incorporating specific chemical moieties enhances MOF functionality.
• Disulfide bonds introduce redox-responsive behavior to MOFs.

Purpose of the Study:

• To review the synthesis and applications of MOFs containing disulfide bonds.
• To highlight the redox-responsive nature of disulfide-containing MOFs.
• To showcase the versatility of these materials in various fields.

Main Methods:

• Literature review of studies reporting disulfide-containing MOFs.
• Analysis of MOF structures and their incorporated disulfide functionalities.
• Compilation of applications demonstrating the utility of these responsive materials.

Main Results:

• Disulfide bonds can be effectively integrated into MOF structures.
• These MOFs exhibit responsiveness to redox stimuli, particularly under reducing conditions.
• Demonstrated applications span drug delivery, ferroptosis induction, exfoliation, energy storage, and chemical sensing.

Conclusions:

• Disulfide-containing MOFs represent a promising class of stimuli-responsive materials.
• Their redox-triggered behavior enables diverse and advanced applications.
• Further research in this area holds potential for innovative technological solutions.