Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pancreas preservation with TP-IV: a hyperosmolar colloid solution.

L H Toledo-Pereyra, G Bock, A Schneider

    Cryobiology
    |February 1, 1985
    PubMed
    Summary

    A new solution, TP-IV, shows promise for preserving canine pancreas grafts. TP-IV outperformed Euro-Collins solution for 72-hour hypothermic storage, achieving survival comparable to fresh grafts.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Diagnosing acute liver graft rejection: experimental application of an implantable telemetric impedance device in native and transplanted porcine livers.

    Biosensors & bioelectronics·2001
    Same author

    Microcell-mediated transfer of chromosome 4 into HeLa cells suppresses telomerase activity.

    Genes, chromosomes & cancer·2001
    Same author

    Fabrication of a single-appointment emergency overdenture using failed fixed prosthetics: a case report.

    Implant dentistry·2001
    Same author

    Quality of life after treatment for early laryngeal carcinoma.

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2001
    Same author

    HPV16 L1E7 chimeric virus-like particles induce specific HLA-restricted T cells in humans after in vitro vaccination.

    International journal of cancer·2001
    Same author

    Endoscopic axillary lymphadenectomy without prior liposuction in 100 patients with invasive breast cancer.

    Surgical laparoscopy, endoscopy & percutaneous techniques·2001

    Area of Science:

    • Transplantation immunology
    • Organ preservation techniques
    • Surgical research

    Background:

    • Hypothermic storage is crucial for pancreas transplantation.
    • Euro-Collins solution is a standard preservation fluid.
    • Long-term graft viability remains a challenge.

    Purpose of the Study:

    • To evaluate the efficacy of a novel hyperosmolar colloid solution (TP-IV) versus Euro-Collins solution.
    • To assess long-term hypothermic storage of canine pancreas autografts for up to 72 hours.

    Main Methods:

    • Canine pancreas autografts were stored hypothermically (4°C) for 72 hours.
    • Grafts were preserved using either Euro-Collins solution or TP-IV.
    • Recipient survival was monitored over a 30-day period.

    Main Results:

    • TP-IV preservation resulted in significantly longer graft survival compared to Euro-Collins solution.
    • Survival rates in the TP-IV group were comparable to those of fresh, non-preserved autografts.
    • Euro-Collins preserved grafts showed reduced survival.

    Conclusions:

    • TP-IV demonstrates superior efficacy for 72-hour hypothermic storage of canine pancreas grafts.
    • This novel solution offers a potential advancement in organ preservation for transplantation.
    • TP-IV may improve outcomes for pancreas transplantation by enhancing graft viability.

    Related Experiment Videos