Decoding Age-Linked Masseter Vestibular Evoked Myogenic Potential Changes in Healthy, Aging Individuals

Area of Science:

• Neuroscience
• Audiology
• Gerontology

Background:

• Vestibular system function declines with age.
• Masseter vestibular evoked myogenic potentials (mVEMPs) are sensitive indicators of vestibular function.
• Age-related changes in vestibular structures are well-documented.

Purpose of the Study:

• To investigate the influence of age on masseter vestibular evoked myogenic potential (mVEMP) parameters.
• To analyze age-related alterations in mVEMP amplitude and latency using 500-Hz tone burst stimuli.
• To establish normative data for mVEMP in different age groups.

Main Methods:

• 110 participants aged 15-60 years were divided into five age groups.
• 500-Hz tone burst stimuli were delivered via air conduction at 125 dB SPL.
• Tukey's honestly significant difference test and multivariate analysis of variance were used for statistical analysis.

Main Results:

• Significant reductions in mVEMP amplitude and prolonged latencies (P11, N21) were observed with increasing age.
• P11 latency was prolonged in younger participants, indicating ongoing maturation.
• Sex differences were noted in P11 latencies but not in other parameters.

Conclusions:

• Age-related degeneration of vestibular sensory hair cells affects mVEMP parameters.
• Age-specific reference data are crucial for accurate diagnosis and interpretation of mVEMP.
• Clinical assessments should incorporate age-correction factors for reliable vestibular function evaluation.