The demonstration of cardiac pathology using perfusion-fixation
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Updated: Aug 18, 2026

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
Published on: November 7, 2019
Abstract:
A simple, cheap and reliable method of perfusion-fixation of hearts is described using readily available domestic water fitments and a pump specifically designed for continuous pumping of corrosive fluids. Hearts fixed in this way readily lend themselves to dissection in echocardiographic planes so that strict correlation with clinical echocardiography may be made. Furthermore it is an excellent way to demonstrate functional valve pathology on post-mortem material.
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