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Updated: Jun 24, 2025
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State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
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First-trimester 3D fetal neurosonography: five standardised views.
Fred Ushakov1, Adalina Sacco1,2, Pranav Pandya1,2
1Fetal Medicine Unit, University College London Hospitals, London, UK.
Summary
This study introduces a specialized first-trimester fetal neurosonography protocol for systematic brain evaluation. It provides key views and pathology examples to aid early detection of fetal brain abnormalities.
Area of Science:
- Medical Imaging
- Fetal Medicine
- Neurosonography
Background:
- Existing international guidelines exist for first-trimester fetal anomaly scans.
- The study addresses the need for a standardized approach to first-trimester fetal brain evaluation.
Purpose of the Study:
- To present a specialist first-trimester fetal neurosonography protocol.
- To illustrate common fetal brain pathologies detectable in early gestation.
Main Methods:
- A retrospective review of 2000 fetal medicine ultrasound scans (2010-2020).
- Utilized a set protocol including 3D transvaginal neurosonography for all cases.
Main Results:
- Proposed five parallel axial views for systematic neurosonography: lateral ventricles, third ventricle, thalamus/mesencephalon, cerebellum, and fourth ventricle.
- Provided examples of fetal brain abnormalities visible in each view.
Conclusions:
- A specialist protocol for systematic first-trimester fetal brain assessment has been presented.
- Further prospective studies are required to evaluate detection rates, reproducibility, and learning curves.
