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Related Concept Videos

Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
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Asepsis01:28

Asepsis

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The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
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Nursing Clinical Information System01:27

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Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
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Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

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Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
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Enhance airway patency
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Nursing Implementation01:15

Nursing Implementation

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Implementation is the execution of the nursing care plan developed during the planning phase.
The five steps to implementing effective nursing care include reassessing the patient, reviewing and revising the existing nursing care plan, organizing the resources and care delivery, anticipating and preventing complications, and implementing nursing interventions.
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Pneumonia IV: Management01:28

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The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
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Related Experiment Video

Updated: Jun 24, 2025

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
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Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

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[Construction and application of sepsis bundle therapy management and practice program].

Yanjie Yang1,2, Xin Gu1, Hu Peng1

  • 1School of Nursing, Xinjiang Medical University, Urumqi 830000, Xinjiang Uygur Autonomous Region, China.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
|June 7, 2024
PubMed
Summary

A new sepsis bundled therapy program improved adherence to treatment protocols and reduced intensive care unit (ICU) stay and costs. This sepsis management strategy shows a trend towards lower 28-day mortality.

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Area of Science:

  • Critical Care Medicine
  • Infectious Diseases
  • Health Services Research

Context:

  • Sepsis remains a leading cause of mortality and morbidity worldwide, necessitating optimized management strategies.
  • Existing sepsis management protocols often face challenges in consistent implementation and adherence.
  • The development of structured, evidence-based bundled interventions is crucial for improving patient outcomes.

Purpose:

  • To construct a comprehensive bundled therapy management and practice program for sepsis.
  • To evaluate the clinical application and effectiveness of this newly developed sepsis protocol.
  • To assess the impact on bundle completion rates, inflammatory markers, and patient outcomes.

Summary:

  • A Delphi-method-based bundled therapy management and practice program for sepsis was developed, comprising 4 primary, 15 secondary, and 34 tertiary indicators.
  • The intervention group, utilizing the new program, demonstrated significantly higher completion rates for 1-hour, 3-hour, and 6-hour sepsis bundles compared to the control group.
  • Patients in the intervention group experienced a significantly shorter ICU length of stay and reduced ICU hospitalization costs, with a non-significant trend towards lower 28-day mortality.

Impact:

  • The implemented sepsis bundled therapy program significantly improved adherence to critical care interventions.
  • The protocol led to a reduction in healthcare resource utilization, evidenced by shorter ICU stays and lower costs.
  • Findings suggest the bundled therapy program is a valuable tool for enhancing sepsis care and potentially reducing mortality.