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Research on coronavirus disease 2019 and the kidney: A bibliometric analysis
Yujiao Wang1, Tingting Chen2, Chunyang Li3
1Division of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, China.
Insights
This study analyzed research on COVID-19 and kidney disease, finding key trends like acute kidney injury (AKI) and kidney transplantation. Understanding these patterns helps guide future research directions in this critical area.
Area of Science:
- Nephrology
- Infectious Diseases
- Bibliometrics
Background:
- Coronavirus disease 2019 (COVID-19) impacts multiple organs, including the kidneys.
- Research on COVID-19's effects on kidney health has significantly increased globally.
- Understanding trends in COVID-19 and kidney disease research is crucial for future directions.
Purpose of the Study:
- To conduct a bibliometric analysis of research on COVID-19 and kidney diseases.
- To identify key research hotspots and evolving trends in this field.
- To provide insights into the development direction of COVID-19 and kidney disease research.
Main Methods:
- Bibliometric analysis of 645 articles published between December 2019 and July 2022.
- Data extracted from the Web of Science database.
- Visualization and statistical analysis using VOSviewer, RStudio, and CiteSpace software.
Main Results:
- The United States and China are leading contributors to research in this field.
- High-frequency keywords include COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), acute kidney injury (AKI), kidney transplant, and mortality.
- Research focus shifted from initial clinical symptoms to associations with chronic kidney disease (CKD), AKI, kidney transplantation, immune response, and vaccines.
Conclusions:
- Bibliometric analysis reveals continuous global attention on COVID-19 and kidney disease.
- Key research hotspots include acute kidney injury (AKI), chronic kidney disease (CKD), kidney transplantation, immune response, and vaccines.
- This analysis highlights the dynamic nature and critical areas of focus in COVID-19's impact on kidney health.
Background:
In addition to damage to the lungs, coronavirus disease 2019 (COVID-19) can damage multiple organs, including the kidney. Our purpose was to analyze the research hotspots and trends in COVID-19 and kidney diseases using bibliometrics to help clarify the development direction of this field.
Methods:
We selected and extracted all relevant publications related to COVID-19 and the kidney from the Web of Science from December 1, 2019, to July 24, 2022. VOSviewer, RStudio, CiteSpace, and other software were used to visualize keywords, publishing trends, authors and their countries, and institutions in this field and perform the statistical analysis.
Results:
A total of 645 articles published in 220 journals were included in this study. The United States and China contributed the most publications and were most active in international cooperation. In addition to COVID-19 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), acute kidney injury (AKI), kidney transplant and mortality were the three keywords with the highest frequencies. In the initial stage of the COVID-19 outbreak, research focused on the clinical symptoms of COVID-19 and other macrocharacteristics, while in a later stage, the associations between SARS-CoV-2 infection and CKD and AKI, as well as the prognosis of patients with kidney disease or those who underwent kidney transplantation, gained more attention. The immune response and vaccines were also recent research hotspots.
Conclusions:
This bibliometric analysis provides a comprehensive overview of research on COVID-19 and kidney disease, which has received continuous, global attention. AKI, CKD, kidney transplantation, immune response and vaccines are among the hotspots in this field.
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