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Updated: Jun 24, 2025

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
Published on: June 1, 2019
Simultaneous Sentinel Lymph Node Biopsies Using Both the Magtrace/Sentimag System and Radioactive Isotope Tracer/Blue
Murtaza Kadhum1, Parinita Swarnkar1, Marianne Dillon2
1Burns and Plastic Surgery, Morriston Hospital, Swansea, Wales, United Kingdom.
Background:
Breast cancer and melanoma are extremely common, with a growing incidence in the United Kingdom. In this case report, we present a patient with synchronous melanoma and breast carcinoma, with focus on the simultaneous use of 2 sentinel lymph node biopsy mapping techniques.
Methods:
The use of 2 mapping techniques in this case is necessary to ensure the accurate identification of the correct sentinel node (for each respective primary malignancy), providing vital prognostic information and allowing for appropriate adjuvant therapy. The report describes the use of a single surgical incision to access both melanoma and breast carcinoma sentinel lymph nodes.
Conclusions:
The report highlights the technical possibility of using both the radioactive isotope tracer/blue dye dual technique and the Magtrace/Sentimag system without interference or complication.
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