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Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

197
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
197
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

132
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
132
Flail Chest-II01:26

Flail Chest-II

165
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
165
  1. Home
  2. Research Domains
  3. Biomedical And Clinical Sciences
  4. Oncology And Carcinogenesis
  5. Predictive And Prognostic Markers
  6. Role Of Extracorporeal Membrane Oxygenation In The Treatment Of Massive Pulmonary Embolism.
  1. Home
  2. Research Domains
  3. Biomedical And Clinical Sciences
  4. Oncology And Carcinogenesis
  5. Predictive And Prognostic Markers
  6. Role Of Extracorporeal Membrane Oxygenation In The Treatment Of Massive Pulmonary Embolism.

Related Experiment Video

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Published on: October 24, 2018

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Role of Extracorporeal Membrane Oxygenation in the Treatment of Massive Pulmonary Embolism.

Hugh A Glazier1, Amir Kaki2,3

  • 1Department of Surgery, University Hospital Galway, Galway, Ireland.

The International Journal of Angiology : Official Publication of the International College of Angiology, Inc
|June 7, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Venoarterial (V-A) extracorporeal membrane oxygenation (ECMO) shows promise for high-risk pulmonary embolism (PE) patients. More research is needed to confirm ECMO

Keywords:
ECMOanticoagulationcardiac arrestextracorporeal life support

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Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
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Related Experiment Videos

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
06:41

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Published on: October 24, 2018

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A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

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Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

283

Area of Science:

  • Cardiology
  • Cardiovascular Surgery
  • Critical Care Medicine

Background:

  • Massive pulmonary embolism (PE) carries a high mortality rate (approx. 65% at 30 days).
  • Renewed interest exists in venoarterial (V-A) extracorporeal membrane oxygenation (ECMO) for high-risk PE treatment.
  • Current evidence on ECMO for massive PE is limited, primarily from retrospective, small, single-center studies without adequate controls.

Purpose of the Study:

  • To review the current evidence and discuss the potential role of V-A ECMO in managing massive PE.
  • To highlight the limitations of existing studies and the need for high-quality research.
  • To explore specific indications for V-A ECMO in massive PE, including cardiac arrest and contraindications to thrombolysis.

Main Methods:

  • Review of existing literature on V-A ECMO for massive PE.
large-bore mechanical thrombectomy
massive pulmonary embolism
right ventricular
thrombolysis
  • Discussion of treatment strategies and patient selection criteria.
  • Identification of knowledge gaps and future research directions.
  • Main Results:

    • V-A ECMO is increasingly supported for massive PE with cardiac arrest.
    • For patients without cardiac arrest but with thrombolysis contraindications, V-A ECMO with anticoagulation can stabilize them.
    • Persistent right ventricular dysfunction after 3-5 days of ECMO may warrant embolectomy.

    Conclusions:

    • High-quality, multicenter, prospective studies are urgently required to establish the definitive role of V-A ECMO in massive PE.
    • V-A ECMO can be a temporizing measure in specific high-risk PE scenarios.
    • Further research is essential to optimize treatment algorithms and improve outcomes for massive PE.