Related Experiment Video

Updated: Jun 24, 2025

Evaluation of Cardiac Contractility Modulation Therapy in 2D Human Stem Cell-Derived Cardiomyocytes
08:47

Evaluation of Cardiac Contractility Modulation Therapy in 2D Human Stem Cell-Derived Cardiomyocytes

Published on: December 16, 2022

2.4K

Proving SGLT2 Inhibitor-Mediated Improvement in Cardiomyocyte Energetics: Beyond a Reasonable Doubt?

Mallory Filipp1, Sanjiv J Shah2

  • 1Department of Pathology (M.F.), Northwestern University Feinberg School of Medicine, Chicago, IL.

Circulation. Heart Failure
|June 7, 2024
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Editorialsheart failuremetabolic diseasemolecular mechanisms of pharmacological actionsodium-glucose transporter 2

More Related Videos

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential
07:41

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential

Published on: January 18, 2019

7.5K
High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers
14:03

High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers

Published on: March 24, 2023

1.8K

Related Experiment Videos

Last Updated: Jun 24, 2025

Evaluation of Cardiac Contractility Modulation Therapy in 2D Human Stem Cell-Derived Cardiomyocytes
08:47

Evaluation of Cardiac Contractility Modulation Therapy in 2D Human Stem Cell-Derived Cardiomyocytes

Published on: December 16, 2022

2.4K
Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential
07:41

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential

Published on: January 18, 2019

7.5K
High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers
14:03

High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers

Published on: March 24, 2023

1.8K

Related Concept Videos

Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

570
Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
570

Articles linked to this work by shared authors, journal, and citation graph.

Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction.

Circulation·2025

Insulin resistance is associated with subclinical myocardial dysfunction and reduced functional capacity in heart failure with preserved ejection fraction.

Journal of cardiology·2023

Hypoxaemia in patients with heart failure and preserved ejection fraction.

European journal of heart failure·2023

Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction According to Polypharmacy Status.

JACC. Heart failure·2023

Design and Baseline Characteristics of STEP-HFpEF Program Evaluating Semaglutide in Patients With Obesity HFpEF Phenotype.

JACC. Heart failure·2023

Update on Atrial Shunt Therapy for Treatment of Heart Failure.

Structural heart : the journal of the Heart Team·2023

Care Models for the Genetic Evaluation of Dilated Cardiomyopathy at Sites of the DCM Consortium.

Circulation. Heart failure·2026

Get With The Guidelines-Heart Failure Hospital Participation and Its Association With Guideline-Directed Medical Therapy and Outcomes.

Circulation. Heart failure·2026

Optimal Strain Combinations for Prognostic Prediction in Pulmonary Arterial Hypertension.

Circulation. Heart failure·2026

Healthcare System Resilience and Adaptation: A 6-Year Analysis of Heart Failure Care in the Veterans Affairs System.

Circulation. Heart failure·2026

Left Atrial Remodeling and Functional Maladaptations in Obesity: An Invasive Pressure-Volume Analysis.

Circulation. Heart failure·2026

Sex Differences in Skeletal Muscle Inflammation and Dysfunction in Patients With Heart Failure and Reduced Ejection Fraction.

Circulation. Heart failure·2026

Cetuximab-loaded self-assembled polymeric nanoparticles for the integrin-targeted therapy of glioblastoma.

JCIS open·2026

Unraveling berberine's multi-target mechanism in combating early-stage masld: a network pharmacology and in vitro study.

Cytotechnology·2026

Iteratively Designed Phospholipid-Targeted Supramolecular Sonosensitizers for Precision Treatment of Pulmonary Infections.

Journal of the American Chemical Society·2026

Cytokine fusion proteins for solid tumor therapy: mechanistic insights and clinical advances.

Journal of hematology & oncology·2026

Multinational Retrospective Chart Review of Treatment Patterns, Clinical Outcomes, and Healthcare Resource Utilization in Solid Organ Transplant Recipients With Refractory/Resistant Cytomegalovirus Infection or Intolerance to Anti-Cytomegalovirus Therapy.

Transplantation proceedings·2026

Glycosomal ABC transporter 3 (GAT3) is associated with antileishmanial drug susceptibility in Leishmania infantum.

Parasitology international·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us