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Updated: Jun 24, 2025

Complete and Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Hemorrhagic Shock
Published on: May 19, 2022
How I manage major hemorrhage.
Jeannie L Callum1,2,3,4, Ronald B George5,6, Keyvan Karkouti5,6
1Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada.
Managing acute hemorrhage requires an individualized approach. Recent advances in protocols, testing, and treatments allow for targeted hemostatic resuscitation, improving patient outcomes in bleeding emergencies.
Area of Science:
- Emergency Medicine
- Hematology
- Critical Care Medicine
Background:
- Acute hemorrhage is a life-threatening emergency with complex management challenges.
- Recent advancements include massive hemorrhage protocols, viscoelastic testing, and new coagulation factors.
- Evidence gaps persist, but sufficient data exists for individualized hemostatic responses.
Purpose of the Study:
- To highlight challenges in acute hemorrhage management through clinical cases.
- To emphasize the importance of interprofessional communication and rapid hemostatic resuscitation.
- To provide a framework for collaboration between clinical teams and hematologists.
Main Methods:
- Presentation of 3 clinical cases illustrating hemorrhage management difficulties.
- Focus on key interventions: hemostatic resuscitation, coagulation monitoring, tranexamic acid, and hemorrhage control.
- Discussion of the collaborative role of hematology in patient care and hospital policy.
Main Results:
- Clinical cases demonstrate the critical need for prompt, targeted hemostatic resuscitation.
- Effective management relies on interprofessional communication and timely interventions.
- Individualized hemostatic strategies are crucial for diverse bleeding patient populations.
Conclusions:
- An individualized hemostatic response, guided by specific defects, is now evidence-based.
- Collaboration between bedside teams and hematology is essential for optimal patient outcomes.
- Hematology services should lead in developing hospital-wide policies for major hemorrhage management.
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