Related Experiment Video
Updated: Jun 24, 2025

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain
Published on: May 7, 2018
Potassium-Based Sodium Substitutes Impact the Sodium and Potassium Content of Foods
Kelly Picard1, Diana R Mager2, Peter A Senior3
1Renal Services, Island Health Authority, Nanaimo, British Columbia, Canada.
Objective:
Potassium-based sodium substitutes (PBSS) can be used to replace sodium during food processing. How potassium and sodium content is associated with PBSS is not known. The objectives of the study were to describe the prevalence of PBSS by sodium content claim category and describe how PBSS are associated with sodium and potassium concentrations by sodium level.
Design And Methods:
This cross-sectional analysis used the July 2018 version of the United States Department of Agriculture's Branded Food Products Database. Products were divided into sodium content claim category and were analyzed for the presence of PBSS. Products with nonmissing values for sodium and potassium were grouped by sodium level and analyzed for the prevalence of PBSS to explore potassium and sodium concentration. Column proportion z-test with the Bonferroni correction was used to explore the occurrence of PBSS by sodium content claim category. Mann-Whitney U-test was used to assess differences in potassium and sodium concentrations across sodium levels and within levels by the presence/absence of PBSS.
Results:
The prevalence of PBSS in the categories "without a sodium content claim" (2.4%), "lightly salted" (0.5%), and "unsalted" claims (0.6%) were statistically significantly lower than prevalence of PBSS in the "sodium free" (9.5%), "low sodium" (10.3%), and "reduced sodium" claim categories (23.3%; all P < .01). Among the group of products with serving sizes more than 30 g containing PBSS, there was a 357 mg per serving higher median sodium concentration and a 160 mg per serving higher median potassium concentration compared to the group without PBSS (both P < .01).
Conclusion:
In the "reduced sodium" claim category, a higher prevalence of PBSS was found compared to other sodium claim categories. The presence of PBSS was associated with higher potassium and sodium concentrations in foods.
More Related Videos
13:14Measuring Fluxes of Mineral Nutrients and Toxicants in Plants with Radioactive Tracers
Published on: August 22, 2014
12:48Measuring Cation Transport by Na,K- and H,K-ATPase in Xenopus Oocytes by Atomic Absorption Spectrophotometry: An Alternative to Radioisotope Assays
Published on: February 19, 2013
Related Concept Videos
Antihypertensive Drugs: Potassium-Sparing Diuretics
Roles of Electrolytes: Sodium and Potassium
Ionic Strength: Effects on Chemical Equilibria
In this solution, the primary...
Regulation of Sodium and Potassium
Sodium Regulation
Sodium ions make up approximately 90% of extracellular cations, with a normal blood plasma concentration of 136–148 mEq/L. A decrease in blood volume and pressure triggers the release of renin from granular cells in the juxtaglomerular complex (JGC), primarily...
Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers
Introduction to Electrolytes
Role of Sodium
One...