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Published on: March 1, 2024
Clinico-mycological characteristics and outcomes of rare yeast infections
Souradeep Chowdhury1, Immaculata Xess2, Manish Soneja3
1Department of Microbiology and Medicine, All India Institute of Medical Sciences, New Delhi, 110029, India.
Abstract:
Unusual fungi, encountered infrequently in practice, present a significant diagnostic challenge, leading to potential delays in diagnosis and treatment. This study aims to describe a number of cases, where infections were caused by rare yeast pathogens. Organisms isolated included rare Candida species, Geotrichum, Lodderomyces and Trichosporon species. The mean duration of the outcome of the patients from microbiological diagnosis was 20 days. A total of 3 patients succumbed to their illness. This study aims to shed light on the varied clinical presentation and outcome of infections caused by rare yeast pathogens.
Insights
Rare yeast infections pose diagnostic challenges, potentially delaying treatment. This study details cases of infections caused by uncommon fungi like Candida, Geotrichum, Lodderomyces, and Trichosporon species.
Area of Science:
- Medical Mycology
- Clinical Microbiology
Background:
- Unusual fungal pathogens are infrequently encountered in clinical practice.
- Rare yeast infections present significant diagnostic challenges, potentially delaying patient treatment and management.
Purpose of the Study:
- To describe clinical presentations and outcomes of infections caused by rare yeast pathogens.
- To highlight the diagnostic difficulties associated with uncommon fungal isolates.
Main Methods:
- Case series describing patients with infections caused by rare yeast pathogens.
- Identification of isolated organisms including rare Candida, Geotrichum, Lodderomyces, and Trichosporon species.
Main Results:
- The mean duration from microbiological diagnosis to outcome was 20 days.
- Three patients (out of the described cases) unfortunately succumbed to their infections.
- Diverse clinical presentations were observed across the cases.
Conclusions:
- Infections by rare yeast pathogens require heightened clinical suspicion and prompt microbiological diagnosis.
- Understanding the varied presentations and outcomes is crucial for effective management of these uncommon infections.

